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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SEPT3
All Species:
20.61
Human Site:
S258
Identified Species:
37.78
UniProt:
Q9UH03
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UH03
NP_061979.3
358
40704
S258
N
D
K
I
R
Q
E
S
M
P
F
A
V
V
G
Chimpanzee
Pan troglodytes
Q5R1W1
434
50272
R240
L
V
K
K
I
K
D
R
L
P
L
A
V
V
G
Rhesus Macaque
Macaca mulatta
XP_001102088
360
40906
S260
N
D
K
I
R
Q
E
S
M
P
F
A
V
V
G
Dog
Lupus familis
XP_857693
357
40495
S257
E
N
D
K
I
R
E
S
M
P
F
A
V
V
G
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z1S5
350
40019
S258
N
D
K
I
R
Q
E
S
M
P
F
A
V
V
G
Rat
Rattus norvegicus
Q9WU34
358
40579
S258
N
D
K
I
R
Q
E
S
M
P
F
A
V
V
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505764
436
49083
M341
V
N
E
K
F
R
E
M
I
P
F
A
V
V
G
Chicken
Gallus gallus
Q5ZMH1
349
40206
N242
P
F
A
V
I
G
S
N
Q
L
I
E
V
K
G
Frog
Xenopus laevis
Q63ZQ1
352
40432
N242
P
F
T
V
V
G
S
N
Q
L
I
E
A
K
G
Zebra Danio
Brachydanio rerio
A2BGU8
361
40623
T269
D
N
D
K
I
R
E
T
M
P
F
A
V
V
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P40797
539
60125
R338
T
T
Q
N
L
R
S
R
V
P
F
A
V
V
G
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_795119
662
73144
Q577
L
N
D
A
L
R
D
Q
M
P
F
A
V
V
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P25342
322
37006
E238
P
F
A
V
V
G
S
E
N
E
I
E
I
N
G
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
38.2
98.8
99.1
N.A.
94.1
98.5
N.A.
54.8
43.2
43.8
77
N.A.
31.1
N.A.
N.A.
34.1
Protein Similarity:
100
56.2
99.1
99.4
N.A.
94.9
99.1
N.A.
65.8
64.5
63.1
85.8
N.A.
45.2
N.A.
N.A.
42.6
P-Site Identity:
100
40
100
60
N.A.
100
100
N.A.
46.6
13.3
6.6
53.3
N.A.
40
N.A.
N.A.
46.6
P-Site Similarity:
100
60
100
73.3
N.A.
100
100
N.A.
73.3
26.6
20
80
N.A.
60
N.A.
N.A.
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
40.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
58.9
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
16
8
0
0
0
0
0
0
0
77
8
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
31
24
0
0
0
16
0
0
0
0
0
0
0
0
% D
% Glu:
8
0
8
0
0
0
54
8
0
8
0
24
0
0
0
% E
% Phe:
0
24
0
0
8
0
0
0
0
0
70
0
0
0
0
% F
% Gly:
0
0
0
0
0
24
0
0
0
0
0
0
0
0
100
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
31
31
0
0
0
8
0
24
0
8
0
0
% I
% Lys:
0
0
39
31
0
8
0
0
0
0
0
0
0
16
0
% K
% Leu:
16
0
0
0
16
0
0
0
8
16
8
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
8
54
0
0
0
0
0
0
% M
% Asn:
31
31
0
8
0
0
0
16
8
0
0
0
0
8
0
% N
% Pro:
24
0
0
0
0
0
0
0
0
77
0
0
0
0
0
% P
% Gln:
0
0
8
0
0
31
0
8
16
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
31
39
0
16
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
31
39
0
0
0
0
0
0
0
% S
% Thr:
8
8
8
0
0
0
0
8
0
0
0
0
0
0
0
% T
% Val:
8
8
0
24
16
0
0
0
8
0
0
0
85
77
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _